On this episode we discuss organophosphate poisoning including nerve agents and insecticides.  Contributors include Matt Zuckerman, Steve Bird, and Adam Darnobid with a shoutout to Jason Hack.

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5 Responses to Episode 7 Organophosphates

  1. Just listened to this talk. Great stuff. More talks like this please.

    Would there be a role for intralipid given the lipophilicity of the various OP compounds?

    Matthew

  2. Steve Bird says:

    Someone asked if intralipid would be useful for acute OP poisoning due to the (often) lipophilic nature of the OPs. That’s a good question. Keep in mind that all of the OPs are different, so it is difficult to generalize. However, we looked at intralipid for parathion poisoning and found that the time until apnea was increased with intralipid, but not much else. Published in Acad Emerg Med. 2012 May;19(5):504-9. doi: 10.1111/j.1553-2712.2012.01337.x.
    Steve

  3. [...] of confirmatory tests are going on to determine if Sarin was used in Syria. This is a follow up to Episode 7 where we talked about the toxicology of organophosphates and nerve agents. Contributors include [...]

  4. [...] or another organophophate nerve gas was used. They previously put together a broader overview on Organophosphates. [...]

  5. […] back… thank goodnes … another episode of Tox Talk is out. In Organophosphates we learn about poisoning from insecticides and nerve agents, and what to you when your patients are […]

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